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Dhat Syndrome encompasses a cluster of symptoms involving sexual, psychological, and physical aspects arising from the discharge of whitish fluid, assumed to be sperm, in urine. This often leads to psychological distress due to perceived sperm loss. Individuals with this syndrome commonly associate it with premature ejaculation, impotence, and seminal fluid leakage during urination. The fear of sperm depletion, particularly intense in the subcontinent, contributes to depression, predominantly affecting young men from rural or lower socioeconomic backgrounds.In addressing the multifaceted nature of Dhat Syndrome, Dr. Erande delve into its historical context while providing modern Dhaturog medicine insights for comprehensive care.